SELECTIVE EGG CELL POLYSPERMY BYPASSES THE TRIPLOID BLOCK

Selective egg cell polyspermy bypasses the triploid block

Polyploidization, the increase in genome copies, Wellingtons is considered a major driving force for speciation.We have recently provided the first direct in planta evidence for polyspermy induced polyploidization.Capitalizing on a novel sco1-based polyspermy assay, we here show that polyspermy can selectively polyploidize the egg cell, while rende

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Assessing the SAfety and FEasibility of bedside portable low-field brain Magnetic Resonance Imaging in patients on ECMO (SAFE-MRI ECMO study): study protocol and first case series experience

Abstract Background To assess the safety and feasibility of imaging of the brain with a point-of-care (POC) magnetic resonance imaging (MRI) system in patients on extracorporeal membrane oxygenation (ECMO).Early detection of acute brain injury (ABI) is critical in improving survival for patients with ECMO support.Methods Patients from a single tert

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The challenge of ovarian tissue culture: 2D versus 3D culture

Abstract Background Cryopreservation of ovarian tissue is a powerful technique for preserving female fertility, as it can restore fertility and endocrine function.To increase the longevity of the transplant and decrease the risk of reimplantation of neoplastic cells, several studies have been carried out with culture of ovarian tissue.The aim of th

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Anxiolytic-like activity of serotonin-3 receptor antagonist: In-silico molecular modeling, drug-likeness and evaluation of anxiolytic activity

Serotonin-3 receptor antagonists have a significant impact in treating nausea and vomiting, and various diseases of the central nervous system.Patients receiving chemotherapy have anxiety as one of their complications.Therefore, we explored the anxiolytic effect of the test compound, 6d {2-[4-(prop-2-en-1-yl)piperazin-1-yl]-1,8-naphthyridine-3-carb

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